If there is a through line to this week's Nose, I would have to call it trespass.
In the remarkable third episode of Louis C.K.'s from-out-of-nowhere filmed theater web series thing "Horace and Pete," the two characters (and there are very nearly only two) played by Laurie Metcalf and C.K. are working out the nature of trespass, as it appears in the Lord's Prayer. As adulterers, they are each trespassers. (But then, we are all trespassers.) And they are both aware that, in trespassing in order to seek pleasure, they create their own hells.